Eventually the need to be unique evolved into the primary theme: a military waging war against the gods of the previous generation. This run started in the shadow of the previous protagonist. The protagonist was a boy named AJDNNW (shortened to AJ). It began on March 2, 2014, and was completed on March 15, 2014. Twitch Plays Pokémon Crystal: The second run in the season, being a sequel using the Generation II game Pokémon Crystal (hacked to make all of Generation 2's 251 Pokémon available in single-player).Achieving victory elevated to protagonist to being legendary. This was conflated with a voting system that came to represent political balance between democracy and anarchy.

Because of the difficulty in coordinating even mundane tasks, successes and failures were attributed to being acts of gods with the iconic Pokemon as their angels. The protagonist was a boy named Red (the default player name). It began on February 13, 2014, and was completed on March 1, 2014.

Twitch Plays Pokémon Red: The first run, done with a (minimally hacked) ROM of the Generation I game Pokémon Red.

For archived progress of the runs, go here. There also is an official Twitter account, available here. The stream's official subreddit can be visited here. It has also spawned many, many snowclones, leading to the creation of a 'Twitch Plays' category on Twitch, one of the most notable being Fish Plays Pokemon, in which a fish plays Pokémon Red.

TPP won the award for 'Best Fan Creation' in the first-ever The Game Awards in 2014, and a Guinness World Record for the most participants on a single-player online video game. The original Streamer stepped down altogether in late 2017, leaving the title of Streamer to Aissurtievos for the last run of Season 4, then to Chaos_Lord after said run ended, to a圆 between Season 7 and 8, and finally to m4_used_rollout in mid-2021. The runs were first hosted by the original Streamer ('TwitchPlaysPokemon' or 'OG Streamer') until DekuNukem hosted them from the first Nintendo 3DS run to the third, after which the stream was hosted by s_SoNick, and finally by m4_used_rollout starting in mid-2017. Of note is that the title of 'Streamer' is usually employed to refer to the person in charge of the stream as a whole, but does not necessarily equate to the person actually hosting it. Additional modes include Commander mode, which automatically determines the next input towards a desired action ('move', 'item', 'switch', 'run'), Military mode, an earlier and less functional version of Commander mode that performed the entire action at once, Congress mode note often referred to simply as a subset of Democracy mode, which is used for sidegames and in which users vote for a single input every few minutes, and Turbo Anarchy, a much-derided mechanic that randomly picked from the last few inputs without break.

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